Nick Nolte portrays Thomas Jefferson, the American founding father and third President of the United States.
Greta Scacchi plays Maria Cosway, an Italian-English artist and musician who had a significant impact on Thomas Jefferson's life.
Thandiwe Newton portrays Sally Hemings, an enslaved woman owned by Thomas Jefferson who is believed to have had a relationship with him.
Gwyneth Paltrow plays Patsy Jefferson, the daughter of Thomas Jefferson and his wife Martha. She accompanies her father to Paris.
Jean-Pierre Aumont appears as D'Hancarville, a French dealer and art historian who is a part of the Parisian social scene.
Simon Callow portrays Richard Cosway, an English portrait painter known for his romantic liaisons and connections with high society.
Seth Gilliam plays James Hemings, the older brother of Sally Hemings, who was also enslaved by Thomas Jefferson and trained as a chef.
James Earl Jones portrays Madison Hemings, the son of Sally Hemings and Thomas Jefferson, who later shared his family's history.
Michael Lonsdale appears as Louis XVI, the King of France during Thomas Jefferson's tenure as the United States Minister to France.
Nancy Marchand plays Madame Abbesse, a character in the Parisian social circle who interacts with Thomas Jefferson and others.
Charlotte de Turckheim portrays Marie Antoinette, the Queen of France during a volatile period leading up to the French Revolution.
Lambert Wilson appears as Marquis de Lafayette, the French aristocrat and military officer who supported the American Revolution and became friends with Thomas Jefferson.
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