Nicolas Cage plays Ben Sanderson, a suicidal alcoholic who forms a complex relationship with a prostitute named Sera.
Elisabeth Shue portrays Sera, a compassionate and understanding prostitute who becomes involved with Ben.
Julian Sands takes on the role of Yuri, a supporting character in Leaving Las Vegas.
Richard Lewis plays Peter, a friend of Ben's who tries to help him but struggles with his own personal issues.
Steven Weber portrays Marc Nussbaum, a character who has a significant impact on the story.
Kim Adams plays Sheila, a minor character in Leaving Las Vegas.
Emily Procter portrays Debbie, a character who appears in the film.
Stuart Regen is Man At Bar in Leaving Las Vegas, a brief but memorable role.
Valeria Golino takes on the role of Terri, a character who plays a part in Ben's journey.
Graham Beckel portrays L.A. Bartender, a character who interacts with Ben during his time in Los Angeles.
Albert Henderson is Man at Strip Bar, a minor character in Leaving Las Vegas.
Shashi Bhatia plays Hispanic Prostitute, a character who has a brief appearance in the film.
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