Jon Voight plays Oscar 'Manny' Manheim, an escaped prisoner determined to break free from his past.
Eric Roberts portrays the character Buck, a fellow escaped prisoner who joins Manny on a dangerous journey.
Rebecca De Mornay takes on the role of Sara, a railway worker who gets caught up in the chaos unfolding on the runaway train.
Kyle T. Heffner plays Frank Barstow, a train dispatcher caught in the middle of the high-stakes situation.
John P. Ryan portrays Ranken, a ruthless warden intent on capturing Manny at any cost.
T.K. Carter is Dave Prince, a train conductor who finds himself facing a life-or-death scenario aboard the runaway locomotive.
Kenneth McMillan takes on the role of Eddie MacDonald, a veteran engineer who must navigate the out-of-control train.
Stacey Pickren portrays Ruby, a young woman caught up in the dangerous situation unfolding on the runaway train.
Walter Wyatt plays Conlan, a railway worker caught in the turmoil aboard the runaway train.
Edward Bunker is Jonah, a fellow prisoner who is also on the run with Manny and Buck.
Reid Cruickshanks portrays Al Turner, a train employee who must deal with the chaos aboard the runaway locomotive.
Dan Wray plays Fat Con, another escaped prisoner who gets entangled in the desperate escape attempt.
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