Neve Campbell portrays Sidney Prescott, the main protagonist who becomes the target of a new killer while attending college.
Courteney Cox plays Gale Weathers, a determined journalist investigating the new string of murders while also revisiting her past experiences.
David Arquette reprises his role as Dewey Riley, the lovable deputy who aids Sidney and Gale in unraveling the mystery behind the killings.
Jerry O'Connell portrays Derek Feldman, a supportive and caring boyfriend to Sidney who gets caught up in the chaos surrounding her.
Timothy Olyphant plays Mickey Altieri, a charismatic and suspicious film student who becomes entangled in the murderous events.
Jamie Kennedy reprises his role as Randy Meeks, the horror movie expert who provides insight into the killer's mindset and motives.
Laurie Metcalf portrays Debbie Salt, a character with a secretive and manipulative nature that adds layers to the unfolding mystery.
Elise Neal plays Hallie McDaniel, a loyal friend of Sidney who finds herself in danger as the killer targets those close to her.
Sarah Michelle Gellar portrays Cici Cooper, a sorority sister who becomes a victim of the killer's deadly game, adding to the suspense.
Liev Schreiber reprises his role as Cotton Weary, a character with a complicated past that resurfaces amidst the new wave of killings.
Jada Pinkett Smith plays Maureen Evans, a character whose actions in the past have lingering effects on the present events of the movie.
Omar Epps portrays Phil Stevens, a character who becomes involved in the dangerous events surrounding the new killer, facing unforeseen consequences.
Our free email delivers the daily top 10 TV shows and top 10 movies directly to your inbox. Stay ahead of the trends. Sign up below.