John Cusack plays the character of John Kelso, a journalist who becomes involved in the mysterious events surrounding a murder in Savannah.
Kevin Spacey portrays James Williams, a wealthy and enigmatic antiques dealer who is at the center of the murder investigation in the film.
Jude Law takes on the role of Billy Carl Hanson, a young and charming hustler who becomes entangled in the dark secrets of Savannah's elite.
Alison Eastwood portrays Mandy Nichols, a character who is caught up in the scandalous events that shake the community of Savannah.
Jack Thompson embodies the character Sonny Seiler, a prominent attorney and dog lover who plays a significant role in the story.
Irma P. Hall brings life to the character Minerva, a wise and respected member of the community who provides insight into the events unfolding in Savannah.
Paul Hipp plays Joe Odom, a colorful and eccentric character who is part of the unique social fabric of Savannah and contributes to the intrigue of the movie.
Lady Chablis portrays Chablis Deveau, a vivacious and bold transgender performer who adds a touch of glamour and mystery to the story of Midnight in the Garden of Good and Evil.
Dorothy Loudon embodies the character Serena Dawes, a key figure in the social scene of Savannah who becomes entangled in the scandal that rocks the city.
Anne Haney portrays Margaret Williams, a character who is part of the upper-class society in Savannah and is drawn into the intrigue surrounding the murder case.
Kim Hunter plays the role of Betty Harty, a no-nonsense and observant character who provides a unique perspective on the events that unfold in the movie.
Geoffrey Lewis portrays Luther Driggers, a memorable and quirky character who adds depth to the eccentric cast of Midnight in the Garden of Good and Evil.
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