Marilyn Chambers plays Rose, the protagonist who undergoes experimental surgery after a motorcycle accident and develops a blood-sucking parasite.
Terri Hanauer portrays Judy Glasberg, a friend of Rose who becomes concerned about the changes she notices in her.
Frank Moore takes on the role of Hart Read, a figure at the plastic surgery clinic where Rose seeks help after her accident.
Joe Silver plays Murray Cypher, another character involved in Rose's treatment and the spread of the parasite.
Howard Ryshpan portrays Dr. Dan Keloid, a doctor who performs the experimental surgery on Rose with unforeseen consequences.
Patricia Gage plays Dr. Roxanne Keloid, the wife of Dr. Keloid who is also involved in the medical procedures.
Susan Roman portrays Mindy Kent, a character caught up in the chaos unleashed by Rose's condition.
Roger Periard plays Lloyd Walsh, a character affected by the events surrounding Rose's transformation.
Lynne Deragon portrays Nurse Louise, a medical professional who witnesses the consequences of the experimental surgery.
Victor Désy plays Claude LaPointe, a character involved in dealing with the aftermath of Rose's condition.
Julie Anna portrays Nurse Rita, another medical professional caught up in the escalating situation.
Gary McKeehan plays Smooth Eddy, a character affected by the events that unfold as a result of Rose's transformation.
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