Ramona and Beezus is a 2010 American animated comedy-drama film based on the Ramona series of novels written by Beverly Cleary. It follows the misadventures of Ramona Quimby, a third-grader with a vivid imagination, as she navigates through the challenges of school and family life. Her antics often involve her older sister, Beezus, and they both discover the importance of self-belief and mutual support.