Ally Sheedy plays Stephanie Speck, a free-spirited animal lover who befriends Number 5.
Steve Guttenberg portrays Newton Crosby, a robotics engineer who creates Number 5.
Fisher Stevens takes on the role of Ben Jabituya, an eccentric and enthusiastic inventor.
Austin Pendleton plays Howard Marner, a paranoid military contractor who wants to capture Number 5.
G.W. Bailey portrays Skroeder, a gruff and no-nonsense military officer.
Brian McNamara plays Frank, a young technician who befriends Number 5.
Tim Blaney provides the voice for Number 5, the intelligent robot who longs to discover the world.
Marvin J. McIntyre plays Duke, a helpful and friendly citizen who encounters Number 5.
John Garber portrays Otis, a mischievous individual involved in a comical incident with Number 5.
Penny Santon plays Mrs. Cepeda, a warm and caring woman who assists the main characters.
Vernon Weddle portrays General Washburne, a military leader involved in the pursuit of Number 5.
Barbara Tarbuck plays Senator Mills, a government official concerned about the actions of Number 5.
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