Michael Keaton plays Billy Caufield, a man who believes he is a doctor named Bickle.
Christopher Lloyd portrays Henry Sikorsky, a former advertising executive with anger management issues.
Peter Boyle takes on the role of Jack McDermott, a former deli owner with a passion for baseball.
Stephen Furst plays Albert Ianuzzi, a man who thinks he is a child in an adult's body.
Dennis Boutsikaris portrays Dr. Weitzman, the psychiatrist assigned to care for the group of men.
Lorraine Bracco plays Riley, a nurse who helps the team navigate the challenges they face.
Milo O’Shea portrays Dr. Newald, a doctor at the psychiatric institution where the team is being held.
Philip Bosco takes on the role of O'Malley, a caring staff member at the institution.
James Remar plays Gianelli, a tough and intimidating character who crosses paths with the team.
Jack Gilpin portrays Dr. Talmer, another doctor involved in the team's care.
MacIntyre Dixon plays Dr. Verboven, a part of the psychiatric team trying to help the men recover.
Michael Lembeck takes on the role of Ed, a member of the group struggling with his own challenges.
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