Dudley Moore plays Wylie Cooper, a character central to the storyline of the movie Best Defense.
Eddie Murphy portrays Lieutenant T.M. Landry in Best Defense.
Kate Capshaw takes on the role of Laura Cooper in the film.
George Dzundza plays the character Steve Loparino in Best Defense.
Helen Shaver portrays Clair Lewis in the movie.
Pamela Stonebrook appears as the Singer in the Rive Gauche Room.
Tom Noonan plays Frank Holtzman in the film Best Defense.
David Paymer's character Kurly adds depth to the ensemble of individuals in the film.
Tracey Ross plays the Arab Girl in Best Defense.
Elizabeth Reiko Kubota appears as the Japanese Singer in the movie.
Paul Comi portrays the Chief Agent in Best Defense.
David Rasche's character Jeff plays a role in the unfolding events of the film.
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