Jack Lemmon plays C.C. Baxter, a mild-mannered insurance worker who lends his apartment out to his superiors for their extramarital affairs.
Shirley MacLaine portrays Fran Kubelik, an elevator operator who becomes romantically involved with C.C. Baxter.
Fred MacMurray takes on the role of Jeff D. Sheldrake, the manipulative head of Baxter's office who also pursues Fran Kubelik.
Ray Walston plays Joe Dobisch, a coworker who takes advantage of Baxter's apartment arrangement.
Jack Kruschen portrays Dr. Dreyfuss, Baxter's neighbor who becomes involved in his personal life.
David Lewis appears as Al Kirkeby, a coworker who is also using Baxter's apartment for his affairs.
Hope Holiday is Mrs. Margie MacDougall, another woman involved with one of Baxter's coworkers.
Joan Shawlee plays Sylvia, a woman who is seen spending time in Baxter's apartment.
Naomi Stevens portrays Mrs. Mildred Dreyfuss, the wife of Dr. Dreyfuss who interacts with Baxter.
Johnny Seven is Karl Matuschka, another tenant in Baxter's apartment building.
Joyce Jameson is The Blonde, a woman who is involved in a love triangle with Baxter and another man.
Willard Waterman plays Mr. Vanderhoff, one of Baxter's coworkers who is also using his apartment for affairs.
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