Cast of The Break-Up

Jennifer Aniston plays Brooke Meyers, a woman who struggles with her relationship as tensions rise with her partner.

Vince Vaughn portrays Gary Grobowski, a man who faces challenges in his romantic life and is affected by the breakup.

Joey Lauren Adams takes on the role of Addie, who becomes involved in the lives of the main characters.

Ann-Margret plays Wendy Meyers, who provides support and guidance to her daughter, Brooke.

Jason Bateman is Riggleman, a friend of Gary who offers advice and commentary throughout the story.

Judy Davis plays Marilyn Dean, who shares insights into relationships, adding perspective to the main couple's struggles.

Vincent D'Onofrio is Dennis Grobowski, Gary's brother, who gets involved in the fallout of the breakup.

Jon Favreau plays Johnny O, a friend who makes light of the situation while providing comic relief.

Cole Hauser portrays Lupus Grobowski, adding to the family dynamic as Gary deals with his breakup.

John Michael Higgins plays Richard Meyers, who contributes to the themes of family relationships in the film.

Justin Long is Christopher, a friend who navigates relationships alongside the main characters.

Ivan Sergei portrays Carson Wigham, who adds to the ensemble cast's exploration of romantic relationships.