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The Fall of the House of Usher is a gothic horror drama television miniseries that intertwines family drama with supernatural elements. The plot focuses on the wealthy and influential siblings, Roderick and Madeline Usher, who run a pharmaceutical empire marked by its troubled legacy. As their tainted past begins to surface, a string of family deaths ensues, seemingly orchestrated by a cryptic woman with ties to their childhood. The show is a modern narrative homage to Edgar Allan Poe's literary works.