Anthony Newley plays Captain Manzini, the owner of an antique shop where the Garbage Pail Kids are accidentally released from a garbage can.
Mackenzie Astin portrays Dodger, a young boy who befriends the mischievous Garbage Pail Kids and tries to protect them from harm.
Katie Barberi takes on the role of Tangerine, a fashion designer who becomes involved in Dodger's adventures with the Garbage Pail Kids.
Phil Fondacaro plays Greaser Greg, one of the Garbage Pail Kids who is always dressed in a leather jacket and sunglasses.
Ron MacLachlan portrays Juice, a member of the Garbage Pail Kids who is known for his love of practical jokes.
J.P. Amateau appears as Wally, a bully who torments Dodger and the Garbage Pail Kids.
Marjory Graue takes on the role of Blythe, a girl who has a crush on Dodger and gets caught up in the chaos caused by the Garbage Pail Kids.
Debbie Lee Carrington provides the voice of Valerie Vomit, one of the Garbage Pail Kids known for her gross and messy habits.
Kevin Thompson voices Ali Gator, a Garbage Pail Kid who has the appearance and habits of an alligator.
Bobby Bell portrays Foul Phil, a Garbage Pail Kid who is always causing mischief and chaos.
Larry Green appears as Nat Nerd, a Garbage Pail Kid who is intelligent but socially awkward.
Arturo Gil provides the voice of Windy Winston, a Garbage Pail Kid who is known for his constant flatulence.
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