Scarlett Johansson portrays Lucy Miller, the titular character in the film who gains superhuman abilities after coming into contact with a powerful synthetic drug.
Morgan Freeman plays Professor Samuel Norman, a renowned academic whose research on human brain capacity becomes pivotal in Lucy's journey.
Choi Min-sik takes on the role of Mr. Jang, a ruthless crime lord whose actions set off the events that lead to Lucy's transformation.
Amr Waked portrays Pierre Del Rio, a French police captain who aids Lucy as she navigates her newfound abilities and seeks retribution.
Julian Rhind-Tutt plays The Limey, a neuroscientist who assists Lucy in understanding and harnessing the powers she acquires.
Pilou Asbæk appears as Richard, a man caught up in Lucy's quest for vengeance and the unfolding chaos resulting from her extraordinary capabilities.
Lio Tipton portrays Caroline, a friend of Lucy who becomes entangled in the dangerous world that Lucy is thrust into.
Shin Yoo-ram takes on the role of Jang's Lieutenant, one of the henchmen working for the antagonist Mr. Jang.
Seo Chong-ju portrays another of Jang's Lieutenants, adding to the opposition that Lucy encounters as her powers grow.
Nicolas Phongpheth appears as Jii, a character who becomes intertwined in Lucy's journey as she grapples with her new reality and abilities.
Paul Lefèvre plays the French Mule, a minor character involved in the criminal underworld that Lucy finds herself up against.
Jan Oliver Schroeder appears as the German Mule, another figure within the criminal network that clashes with Lucy on her path to seeking justice.
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