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My Sister's Keeper
Cast
36 cast members · 20 with popularity data
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Sorted by Buzz Score · May 13, 2026
1
Cameron Diaz
Sara Fitzgerald
6.1
#450 overall
2
Alec Baldwin
Campbell Alexander
4.8
#707 overall
3
Emily Deschanel
Dr. Farquad
2.5
#2,027 overall
4
Abigail Breslin
Andromeda "Anna" Fitzgerald
1.9
#2,866 overall
5
Joan Cusack
Judge De Salvo
1.9
#2,939 overall
6
Jason Patric
Brian Fitzgerald
1.7
#3,278 overall
7
Rick Salomon
Bailiff Bert
1.7
#3,374 overall
8
Lin Shaye
Nurse Adele
1.1
#5,536 overall
9
E. G. Daily
Nurse Susan
0.9
#6,506 overall
10
David Thornton
Dr. Chance
0.9
#6,665 overall
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11
Mary Jo Deschanel
Saleswoman
0.5
#9,998 overall
12
Thomas Dekker
Taylor Ambrose
0.3
#13,707 overall
13
Michael Chow
Dr. Chow
0.3
#14,101 overall
14
Sofia Vassilieva
Kate Fitzgerald
0.3
#15,362 overall
15
Marcos A. Ferraez
EMT
0.2
#19,641 overall
16
Evan Ellingson
Jesse Fitzgerald
0.1
#22,378 overall
17
Heather Wahlquist
Aunt Kelly
0.1
#26,836 overall
18
Ellia English
Nurse Alice
0.1
#28,326 overall
19
Nicole Marie Lenz
Gloria
0.0
#44,076 overall
20
Annie Wood
Uncle Tommy's Wife
0.0
#55,776 overall
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21
Frank Cassavetes
Gus
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22
Chris Kinkade
Dr. Nguyen
—
23
Jeffrey Markle
Dr. Wayne
—
24
Frank Peluso
Bailiff #2
—
25
Rico Simonini
Process Server
—
26
Keith Kraft
Paramedic (uncredited)
—
27
Nina Barry
Miss Swearingen
—
28
Paul Butler
Jesse age 3
—
29
Walter Raney
Pawn Shop Proprietor
—
30
John DeRosa
EMT
—
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31
Noni Tulk-Perna
Ellen
—
32
Matthew Barry
Uncle Tommy
—
33
David Bortolucci
Harry
—
34
Andrew Schaff
Nurse Stephen
—
35
Mimi Fletcher
De Salvo's Secretary
—
36
Kaleti Williams
Bouncer (uncredited)
—
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