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My Sister's Keeper
Cast
36 cast members · 20 with popularity data
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Sorted by Buzz Score · April 23, 2026
1
Cameron Diaz
Sara Fitzgerald
5.7
#447 overall
2
Alec Baldwin
Campbell Alexander
4.7
#668 overall
3
Emily Deschanel
Dr. Farquad
2.8
#1,660 overall
4
Abigail Breslin
Andromeda "Anna" Fitzgerald
2.2
#2,315 overall
5
Joan Cusack
Judge De Salvo
1.6
#3,381 overall
6
Jason Patric
Brian Fitzgerald
1.3
#4,205 overall
7
Rick Salomon
Bailiff Bert
1.0
#5,419 overall
8
Lin Shaye
Nurse Adele
0.7
#7,439 overall
9
E. G. Daily
Nurse Susan
0.7
#7,731 overall
10
David Thornton
Dr. Chance
0.5
#9,652 overall
11
Mary Jo Deschanel
Saleswoman
0.5
#10,496 overall
12
Sofia Vassilieva
Kate Fitzgerald
0.4
#11,215 overall
13
Thomas Dekker
Taylor Ambrose
0.3
#13,841 overall
14
Marcos A. Ferraez
EMT
0.3
#15,120 overall
15
Evan Ellingson
Jesse Fitzgerald
0.2
#16,676 overall
16
Michael Chow
Dr. Chow
0.2
#17,345 overall
17
Heather Wahlquist
Aunt Kelly
0.1
#24,715 overall
18
Ellia English
Nurse Alice
0.1
#26,198 overall
19
Nicole Marie Lenz
Gloria
0.0
#48,937 overall
20
Annie Wood
Uncle Tommy's Wife
0.0
#52,272 overall
21
Frank Cassavetes
Gus
—
22
Chris Kinkade
Dr. Nguyen
—
23
Jeffrey Markle
Dr. Wayne
—
24
Frank Peluso
Bailiff #2
—
25
Rico Simonini
Process Server
—
26
Keith Kraft
Paramedic (uncredited)
—
27
Nina Barry
Miss Swearingen
—
28
Paul Butler
Jesse age 3
—
29
Walter Raney
Pawn Shop Proprietor
—
30
John DeRosa
EMT
—
31
Noni Tulk-Perna
Ellen
—
32
Matthew Barry
Uncle Tommy
—
33
David Bortolucci
Harry
—
34
Andrew Schaff
Nurse Stephen
—
35
Mimi Fletcher
De Salvo's Secretary
—
36
Kaleti Williams
Bouncer (uncredited)
—
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