Cast of I Am Legend

Portrays Robert Neville, a virologist who survives a deadly pandemic and becomes the last human in New York City.

Plays Anna Montez, a survivor who encounters Neville and provides a glimmer of hope for a cure.

Portrays Ethan, a young survivor accompanying Anna who also meets Neville.

Portrays the Alpha Male, a mutated, aggressive leader of the Darkseekers, who are infected humans.

Plays Zoe Neville, Robert Neville's wife who appears in flashbacks throughout the film.

Portrays Marley Neville, the daughter of Robert Neville, also seen in flashbacks.

Portrays Dr. Alice Krippin, a scientist who appears in a broadcast explaining her role in the creation of the virus responsible for the global pandemic.

Plays Mike, a military escort participating in the evacuation and protection operations in the film.

Plays the Alpha Female, another leading Darkseeker who displays unprecedented levels of intelligence and aggression.

Plays Military Driver Jay, one of the military personnel involved in coordination during the crisis.

Plays the Sergeant, a member of the military forces involved in the city's evacuation.

Plays Woman Evacuee, one of the civilians attempting to flee the chaos as the pandemic spreads.