Anne Parillaud plays Nikita / Marie Clément, the protagonist of the film who transforms from a criminal to a skilled assassin.
Jean-Hugues Anglade portrays Marco, an important character in Nikita's life.
Tchéky Karyo takes on the role of Bob, a key figure in Nikita's training and missions.
Jean Reno appears as Victor, known as the 'cleaner', a mysterious and skilled operative.
Marc Duret plays Rico, a character intertwined in Nikita's world.
Jeanne Moreau portrays Armande, adding depth to the story.
Patrick Fontana takes on the role of Coyotte, a character with significance in the storyline.
Roland Blanche appears as Interrogation Cop, a role crucial for the development of the plot.
Jacques Boudet plays The Pharmacist, a character with a specific role in the narrative.
Jean Bouise appears as The Embassy Attaché, adding to the complexity of the storyline.
Philippe du Janerand takes on the characters of The Ambassador and Jules, his double.
Alain Lathière plays Zap, contributing to the ensemble of characters in the film.
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