Only the Lonely Cast

John Candy plays Danny Muldoon, a kind-hearted Chicago policeman who struggles to balance his devotion to his overbearing mother with finding love.

Maureen O'Hara portrays Rose Muldoon, Danny's widowed, strong-willed mother who disapproves of his romantic relationships.

Ally Sheedy stars as Theresa Luna, a mortician who becomes romantically involved with Danny, causing tension in his family.

Kevin Dunn plays Patrick Muldoon, Danny's older brother who constantly tries to meddle in his affairs.

Milo O’Shea portrays Doyle, a close friend of Rose who disapproves of Danny's choices.

Bert Remsen plays Spats, Danny's coworker and friend who offers him advice on relationships.

Anthony Quinn appears as Nick Acropolis, a restaurateur who befriends Danny and offers him encouragement.

Jim Belushi portrays Salvatore Buonarte, a family friend of the Muldoons who tries to help Danny navigate his love life.

Joe Greco plays Johnny Luna, Theresa's overprotective brother who disapproves of her relationship with Danny.

Marvin J. McIntyre appears as Father Strapovic, a priest who offers guidance to Danny in times of need.

Macaulay Culkin portrays Billy Maldoon, Danny's teenage nephew who provides comedic relief in the family drama.

Kieran Culkin plays Patrick Muldoon Jr., Danny's young nephew who looks up to his uncle despite the family's disapproval of his love life.