Gene Wilder plays Stanley, a protagonist who struggles with the transformation of his town's residents into rhinoceroses.
Zero Mostel portrays John, a friend of Stanley's who undergoes the same unsettling metamorphosis into a rhinoceros.
Karen Black takes on the role of Daisy, a character who reacts to the surreal events unfolding in the town.
Joe Silver plays Norman, a resident who is affected by the mysterious rhinoceros transformations happening around him.
Robert Weil portrays Carl, a secondary character who witnesses the bizarre occurrences in the town.
Marilyn Chris is Mrs. Bingham, a character who experiences the surreal transformation of the townspeople into rhinoceroses.
Percy Rodriguez portrays Mr. Nicholson, a resident who grapples with the unusual events taking place in the town.
Robert Fields plays the Young Man, a character who is affected by the strange happenings in the town.
Melody Santangello portrays the Young Woman, a character who witnesses the unsettling transformation of the townspeople.
Don Calfa plays the role of the Waiter, a minor character who interacts with the main cast during the unfolding events.
Lou Cutell portrays the Cashier, a character who is part of the town's environment affected by the mysterious transformations.
Howard Morton is the Doctor, a character who tries to make sense of the strange occurrences happening within the town.
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