Jane Alexander portrays Carol Wetherly, the matriarch of the Wetherly family, who must find ways to keep her family together in the post-apocalyptic world.
William Devane takes on the role of Tom Wetherly, the husband of Carol and father figure trying to protect his family and cope with the challenges of the new world.
Ross Harris plays Brad Wetherly, one of the Wetherly children who must adapt to the harsh realities of a world consumed by the aftermath of a nuclear disaster.
Roxana Zal portrays Mary Liz Wetherly, one of the younger members of the family who must grow up quickly in order to survive the new post-apocalyptic environment.
Lukas Haas plays Scottie Wetherly, another one of the children in the Wetherly family, who learns to navigate the challenges of the new world alongside his family.
Philip Anglim appears as Hollis, a character who interacts with the Wetherly family and becomes a part of their support system in the midst of the unfolding tragedy.
Lilia Skala takes on the role of Fania, a character who provides comfort and wisdom to the Wetherly family during their struggles in the aftermath of the nuclear attack.
Leon Ames portrays Henry Abhart, a character who grapples with the implications of the nuclear disaster and seeks to find ways to rebuild and survive in the new world.
Lurene Tuttle plays Rosemary Abhart, a character who faces the challenges of a world forever changed by nuclear devastation alongside her family and community.
Rebecca De Mornay portrays Cathy Pitkin, a character who navigates the complexities of the new post-apocalyptic world and forms connections with the Wetherly family.
Kevin Costner plays Phil Pitkin, a character who becomes involved in the lives of the Wetherly family as they struggle to survive in a world altered by a nuclear catastrophe.
Mako appears as Mike, a character who interacts with the Wetherly family and plays a role in their journey to adapt and cope with the aftermath of the nuclear attack.
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