Jason Miller portrays Father Damien Karras, a young priest who is struggling with his faith and is tasked with performing an exorcism on a young girl named Regan.
Ellen Burstyn plays Chris MacNeil, the mother of Regan MacNeil, who desperately seeks help for her daughter as she witnesses her disturbing and inexplicable behavior.
Linda Blair takes on the role of Regan MacNeil, a sweet and innocent young girl who becomes possessed by a malevolent force, leading to terrifying and grotesque transformations.
Max von Sydow portrays Father Lankester Merrin, an experienced and wise priest who has previously encountered the demon Pazuzu and is called upon to help perform the exorcism.
Lee J. Cobb plays Lt. Bill Kinderman, a detective investigating the mysterious death of a film director in a case that becomes intertwined with Regan's possession.
Kitty Winn is Sharon Spencer, a kind and supportive assistant to Chris MacNeil who witnesses the horrors of Regan's possession and provides moral support.
Jack MacGowran portrays Burke Dennings, a film director and friend of Chris MacNeil who meets a tragic end as a result of the demonic forces at play.
William O'Malley plays Father Joseph Kevin Dyer, a young and compassionate priest who assists Father Karras in the exorcism ritual and provides spiritual guidance.
Barton Heyman is Dr. Klein, a medical professional who initially tries to explain Regan's condition through scientific means before the supernatural nature of her possession becomes apparent.
Peter Masterson plays Dr. Barringer, a psychiatrist who is consulted to evaluate Regan's mental state and behavior as her possession worsens.
Rudolf Schündler is Karl, a German butler employed by the MacNeil family who witnesses the disturbing events surrounding Regan's possession.
Gina Petrushka plays Willi, a housekeeper working for the MacNeil family who is deeply affected by the frightening occurrences tied to Regan's possession.
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