Jeff Goldblum portrays Seth Brundle, a brilliant but eccentric scientist who becomes a human-fly hybrid.
Geena Davis plays Veronica Quaife, a journalist who becomes entangled in Seth Brundle's tragic transformation.
John Getz is Stathis Borans, an editor and ex-boyfriend of Veronica who tries to protect her from the danger posed by Brundle's experiment.
Joy Boushel portrays Tawny, a minor character in the film.
Leslie Carlson plays Dr. Brent Cheevers, a supporting character in the movie.
George Chuvalo is Marky, a minor character in the film.
Michael Copeman plays the 2nd Man in Bar, a brief role in the movie.
David Cronenberg appears as the Gynecologist in a small role.
Carol Lazare appears as the Nurse, a minor character in the film.
Shawn Hewitt portrays the Clerk in a minor role.
Typhoon is the Baboon, a character whose role is uncredited in the film.
Ann Green appears as a Restaurant Patron in an uncredited role.
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