Ron Fazio plays The Toxic Avenger and also portrays the Apocalypse Inc. Executive, a character involved in the corporate side of the storyline.
John Altamura plays The Toxic Avenger, a superhero who fights against evil forces.
Phoebe Legere plays Claire, a central character who is connected to The Toxic Avenger.
Rick Collins portrays the Apocalypse Inc. Chairman, a villainous character overseeing the company.
Rikiya Yasuoka plays Big Mac Bunko, a character involved in the story's conflict.
Tsutomu Sekine serves as the Announcer, providing commentary throughout the movie.
Lisa Gaye plays Malfaire, a character representing the antagonistic forces in the film.
Jessica Dublin portrays Mrs. Junko, a character contributing to the film's comedic elements.
Mayako Katsuragi plays Masami, adding to the ensemble cast of the movie.
Shinoburyû portrays Shôchikuyama, a character who plays a role in the narrative.
Erika Schickel plays the Psychiatrist, a character providing a psychological perspective in the film.
Michael Jai White portrays another Apocalypse Inc. Executive, participating in the corporate intrigue.
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