How to Die Alone is an American comedy series featuring Natasha Rothwell as Mel, a disillusioned JFK airport worker. The show traces Mel's transformative journey from a life of unfulfilled dreams and lovelessness, spurred by a near-death experience. With humor and heart, Mel decides to embrace life's possibilities and overcome her personal limitations. The series combines the everyday with the extraordinary, depicting Mel's aspirations and struggles in a lively and empathetic manner.