Cast of WHAT / IF

Renée Zellweger portrays Anne Montgomery, a wealthy and powerful woman who makes Lisa the life-changing proposition. Zellweger is an American actress who has won several awards, including an Academy Award for her role in the film 'Cold Mountain'.

Jane Levy portrays Lisa Ruiz-Donovan, a talented scientist who is confronted with a life-altering proposal that tests her values and morals. Levy is an American actress known for her roles in television shows such as 'Suburgatory' and 'Castle Rock'.

Blake Jenner plays the character of Sean Donovan, Lisa's husband and a passionate baseball player who dreams of making it big. Jenner is an American actor known for his work in the musical television series 'Glee' and the film 'Everybody Wants Some!!'.

Keith Powers portrays Todd Archer, a close friend of Lisa and Sean. Todd is ambitious and has a knack for business. Powers is an American actor and model who has appeared in films such as 'Straight Outta Compton' and the television series 'Famous in Love'.

Samantha Marie Ware plays Angela Archer, Todd's girlfriend and an aspiring singer. Angela is determined to achieve success in her music career. Ware is an American actress and singer who gained recognition for her role in the musical television series 'Glee'.

Juan Castano takes on the role of Marcos Ruiz, Lisa's brother and a police officer. Marcos is protective of his sister and is torn between duty and family. Castano is a Colombian-American actor known for his performances in the play 'Transfers' and the television series 'The OA'.

Bonnie Bedelia appears as Margaret, Lisa's adoptive mother who has her own secrets and past. Bedelia is an American actress known for her roles in films like 'Die Hard' and 'Heart Like a Wheel'.

Simon Hunt plays Sergeant Miller, a police officer who becomes involved in the unfolding events. Hunt is an actor known for his work in television shows such as 'Killing Eve' and 'Strike Back'.