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Annihilation

Annihilation Cast

19 cast members · 12 with popularity data
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Most Popular Annihilation Cast Members

Natalie Portman is currently the most popular Annihilation cast member online with a Attention Score of 28.1. 2 of 19 cast members rank in the top 1,000 actors online today. Updated September 6, 2026.

1
Natalie Portman
Lena
28.1
#19 overall
2
Oscar Isaac
Kane
5.2
#851 overall
3
Tessa Thompson
Josie Radek
4.1
#1,341 overall
4
Jennifer Jason Leigh
Dr Ventress
4.0
#1,381 overall
5
Cosmo Jarvis
Special Ops Soldier (uncredited)
2.6
#2,482 overall
6
Benedict Wong
Lomax
2.3
#2,933 overall
7
Sonoya Mizuno
Humanoid / Katie (Med Student)
1.7
#4,222 overall
8
Tuva Novotny
Cass Sheppard
1.4
#5,371 overall
9
Gina Rodriguez
Anya Thorensen
1.3
#5,499 overall
10
David Gyasi
Daniel
0.5
#11,736 overall
11
Kola Bokinni
Peyton (uncredited)
0.5
#12,610 overall
12
John Schwab
Paramedic
0.1
#30,234 overall
13
Sammy Hayman
Mayer
—
14
Josh Danford
Shelley
—
15
Kristen McGarrity
Lena Double
—
16
Kumud Pant
Scientist
—
17
Honey Holmes
Scientist (uncredited)
—
18
Hiten Patel
Scientist (uncredited)
—
19
Matthew Simpson
Special Ops Soldier (uncredited)
—
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