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Annihilation

Annihilation Cast

19 cast members · 12 with popularity data
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Sorted by Buzz Score · June 16, 2026
1
Natalie Portman
Lena
6.5
#328 overall
2
Oscar Isaac
Kane
3.5
#1,087 overall
3
Jennifer Jason Leigh
Dr Ventress
3.2
#1,297 overall
4
Tessa Thompson
Josie Radek
2.3
#2,067 overall
5
Sonoya Mizuno
Humanoid / Katie (Med Student)
1.5
#3,472 overall
6
Benedict Wong
Lomax
1.1
#4,825 overall
7
Gina Rodriguez
Anya Thorensen
1.1
#4,981 overall
8
Tuva Novotny
Cass Sheppard
1.0
#5,648 overall
9
Cosmo Jarvis
Special Ops Soldier (uncredited)
0.8
#6,679 overall
10
Kola Bokinni
Peyton (uncredited)
0.4
#12,458 overall
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11
David Gyasi
Daniel
0.4
#12,881 overall
12
John Schwab
Paramedic
0.1
#32,975 overall
13
Sammy Hayman
Mayer
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14
Josh Danford
Shelley
—
15
Kristen McGarrity
Lena Double
—
16
Kumud Pant
Scientist
—
17
Honey Holmes
Scientist (uncredited)
—
18
Hiten Patel
Scientist (uncredited)
—
19
Matthew Simpson
Special Ops Soldier (uncredited)
—
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