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Annihilation
Cast
19 cast members · 12 with popularity data
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Sorted by Buzz Score · May 28, 2026
1
Natalie Portman
Lena
6.9
#346 overall
2
Oscar Isaac
Kane
6.1
#432 overall
3
Jennifer Jason Leigh
Dr Ventress
3.8
#1,052 overall
4
Tessa Thompson
Josie Radek
2.1
#2,481 overall
5
Gina Rodriguez
Anya Thorensen
1.2
#4,844 overall
6
Benedict Wong
Lomax
1.2
#4,875 overall
7
Cosmo Jarvis
Special Ops Soldier (uncredited)
1.1
#5,236 overall
8
Sonoya Mizuno
Humanoid / Katie (Med Student)
1.1
#5,506 overall
9
Tuva Novotny
Cass Sheppard
0.8
#7,124 overall
10
David Gyasi
Daniel
0.4
#13,084 overall
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11
Kola Bokinni
Peyton (uncredited)
0.3
#15,524 overall
12
John Schwab
Paramedic
0.1
#31,706 overall
13
Sammy Hayman
Mayer
—
14
Josh Danford
Shelley
—
15
Kristen McGarrity
Lena Double
—
16
Kumud Pant
Scientist
—
17
Honey Holmes
Scientist (uncredited)
—
18
Hiten Patel
Scientist (uncredited)
—
19
Matthew Simpson
Special Ops Soldier (uncredited)
—
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