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Annihilation

Annihilation Cast

19 cast members · 12 with popularity data
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Most Popular Annihilation Cast Members

Natalie Portman is currently the most popular Annihilation cast member online with a Attention Score of 7.8. 1 of 19 cast members rank in the top 1,000 actors online today. Updated October 3, 2026.

1
Natalie Portman
Lena
7.8
#395 overall
2
Oscar Isaac
Kane
4.5
#1,072 overall
3
Jennifer Jason Leigh
Dr Ventress
3.7
#1,491 overall
4
Tessa Thompson
Josie Radek
3.5
#1,602 overall
5
Cosmo Jarvis
Special Ops Soldier (uncredited)
3.4
#1,617 overall
6
Benedict Wong
Lomax
1.9
#3,607 overall
7
Gina Rodriguez
Anya Thorensen
1.8
#3,686 overall
8
Tuva Novotny
Cass Sheppard
1.4
#4,898 overall
9
Sonoya Mizuno
Humanoid / Katie (Med Student)
1.4
#4,899 overall
10
David Gyasi
Daniel
0.7
#9,155 overall
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11
Kola Bokinni
Peyton (uncredited)
0.4
#13,779 overall
12
John Schwab
Paramedic
0.1
#30,850 overall
13
Sammy Hayman
Mayer
—
14
Josh Danford
Shelley
—
15
Kristen McGarrity
Lena Double
—
16
Kumud Pant
Scientist
—
17
Honey Holmes
Scientist (uncredited)
—
18
Hiten Patel
Scientist (uncredited)
—
19
Matthew Simpson
Special Ops Soldier (uncredited)
—
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