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Annihilation

Annihilation Cast

19 cast members · 12 with popularity data
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Sorted by Buzz Score · July 2, 2026
1
Natalie Portman
Lena
4.7
#634 overall
2
Sonoya Mizuno
Humanoid / Katie (Med Student)
4.0
#844 overall
3
Oscar Isaac
Kane
3.8
#912 overall
4
Tessa Thompson
Josie Radek
3.2
#1,237 overall
5
Jennifer Jason Leigh
Dr Ventress
2.8
#1,466 overall
6
Benedict Wong
Lomax
1.2
#4,487 overall
7
Gina Rodriguez
Anya Thorensen
1.0
#5,369 overall
8
Tuva Novotny
Cass Sheppard
0.8
#6,685 overall
9
Cosmo Jarvis
Special Ops Soldier (uncredited)
0.8
#6,863 overall
10
Kola Bokinni
Peyton (uncredited)
0.3
#14,072 overall
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11
David Gyasi
Daniel
0.3
#14,388 overall
12
John Schwab
Paramedic
0.0
#39,858 overall
13
Sammy Hayman
Mayer
—
14
Josh Danford
Shelley
—
15
Kristen McGarrity
Lena Double
—
16
Kumud Pant
Scientist
—
17
Honey Holmes
Scientist (uncredited)
—
18
Hiten Patel
Scientist (uncredited)
—
19
Matthew Simpson
Special Ops Soldier (uncredited)
—
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