Robin Williams portrays Professor Philip Brainard, a scatterbrained but brilliant inventor who creates a bouncy, flying rubber substance called Flubber.
Marcia Gay Harden plays Dr. Sara Jean Reynolds, Professor Brainard's supportive fiancee who is also a fellow scientist.
Christopher McDonald takes on the role of Wilson Croft, the villainous businessman trying to steal Professor Brainard's invention.
Raymond J. Barry portrays Chester Hoenicker, the overbearing father of one of Brainard's students who gets involved in the chaos caused by Flubber.
Clancy Brown is Smith, one of Croft's henchmen who assists in the schemes to steal Flubber.
Nancy Olson appears as the Secretary at Ford Motor Company, a character entangled in the pursuit of Flubber's secrets.
Ted Levine plays Wesson, another one of Croft's henchmen aiding in the mission to get hold of Flubber.
Wil Wheaton takes on the role of Bennett Hoenicker, Chester's son who becomes one of the first victims of Flubber's mischievous effects.
Edie McClurg portrays Martha George, a character within the community impacted by the wild and unpredictable behavior caused by Flubber.
Jodi Benson provides the voice for Weebo, Professor Brainard's loyal and intelligent robotic assistant.
Leslie Stefanson appears as Sylvia, a character caught up in the chaos that ensues due to Flubber's unpredictable nature.
Malcolm Brownson plays the Father, a minor character impacted by the events surrounding Flubber.
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