Machete Kills Cast
The cast of Machete Kills including popularity data. Data for April 18, 2025.
Danny Trejo
as Machete Cortez

Danny Trejo plays the titular character Machete Cortez.

#11
Most popular actor on Machete Kills
2,949 Wikipedia views yesterday
Mel Gibson
as Luther Voz

Mel Gibson takes on the role of Luther Voz.

#5
Most popular actor on Machete Kills
10,778 Wikipedia views yesterday
Demián Bichir
as Mendez

Demián Bichir portrays the character Mendez.

#16
Most popular actor on Machete Kills
550 Wikipedia views yesterday
Amber Heard
as Blanca Vasquez / Miss San Antonio

Amber Heard embodies the characters Blanca Vasquez / Miss San Antonio.

#6
Most popular actor on Machete Kills
7,063 Wikipedia views yesterday
Michelle Rodriguez
as Luz

Michelle Rodriguez portrays the character Luz.

#13
Most popular actor on Machete Kills
2,843 Wikipedia views yesterday
Sofía Vergara
as Desdemona

Sofía Vergara takes on the role of Desdemona.

#8
Most popular actor on Machete Kills
5,902 Wikipedia views yesterday
Charlie Sheen
as Mr. President

Charlie Sheen appears as Mr. President.

#4
Most popular actor on Machete Kills
12,165 Wikipedia views yesterday
Jessica Alba
as Sartana Rivera

Jessica Alba brings the character Sartana Rivera to life.

#7
Most popular actor on Machete Kills
6,539 Wikipedia views yesterday
Lady Gaga
as La Camaleon
#3
Most popular actor on Machete Kills
20,295 Wikipedia views yesterday
Alexa PenaVega
as KillJoy
#14
Most popular actor on Machete Kills
2,025 Wikipedia views yesterday
Vanessa Hudgens
as Cereza Desdemona
#10
Most popular actor on Machete Kills
3,984 Wikipedia views yesterday
Tom Savini
as Osiris Amanpour
#17
Most popular actor on Machete Kills
434 Wikipedia views yesterday
Cuba Gooding Jr.
as El Camaleon
#12
Most popular actor on Machete Kills
2,899 Wikipedia views yesterday
Antonio Banderas
as El Camaleon
#9
Most popular actor on Machete Kills
4,645 Wikipedia views yesterday
Walton Goggins
as El Camaleon
#2
Most popular actor on Machete Kills
25,690 Wikipedia views yesterday
William Sadler
as Sheriff Doakes
Marko Zaror
as Zaror
#18
Most popular actor on Machete Kills
354 Wikipedia views yesterday
Julio Oscar Mechoso
as Chepo
#20
Most popular actor on Machete Kills
156 Wikipedia views yesterday
Billy Blair
as Billy
Samuel Davis
as Clebourne
Felix Sabates
as Doc Felix
Electra Avellan
as Nurse Mona
Elise Avellan
as Nurse Lisa
Marci Madison
as Nurse Fine
Callie Hernandez
as Space Babe
#19
Most popular actor on Machete Kills
209 Wikipedia views yesterday
Alejandro Antonio
as Boss of Mendez
Crystal Martinez
as Wife of Mendez
Corey Burton
as Trailer Voice Guy (voice)
#15
Most popular actor on Machete Kills
573 Wikipedia views yesterday
Elon Musk
as Elon Musk
#1
Most popular actor on Machete Kills
46,506 Wikipedia views yesterday
Emmy Robbin
as Pris
Jason Christopher
as Lieutenant Brass
Sam Medina
as Cartel Leader
J.J. Perry
as Voz's Henchman (uncredited)
Aleksander Rodnyansky
as Radio Guest (uncredited)
For the best insights and data about Machete Kills, visit our main Machete Kills page.