The Astronaut's Wife Cast
The cast of The Astronaut's Wife.
Johnny Depp
as Commander Spencer Armacost

Johnny Depp plays Commander Spencer Armacost, an astronaut who experiences a life-altering event during a space mission.

Charlize Theron
as Jillian Armacost

Charlize Theron portrays Jillian Armacost, the wife of Commander Armacost, who struggles with the changes in her husband after his return from space.

Joe Morton
as Sherman Reese

Joe Morton plays Sherman Reese, a NASA official who is involved in the investigation of the astronaut's mysterious transformation.

Clea DuVall
as Nan

Clea DuVall plays Nan, a friend of Jillian Armacost who becomes concerned about the troubling changes in her life.

Nick Cassavetes
as Captain Alex Streck

Nick Cassavetes portrays Captain Alex Streck, a fellow astronaut and colleague of Spencer.

Donna Murphy
as Natalie Streck

Donna Murphy plays Natalie Streck, who is connected to the personal and emotional aspects of the astronauts' lives.

Gary Grubbs
as NASA Director

Gary Grubbs portrays the NASA Director, who oversees the operations and management of the space mission.

Blair Brown
as Shelly McLaren

Blair Brown plays Shelly McLaren, who interacts with the main characters throughout the storyline.

Tom Noonan
as Jackson McLaren

Tom Noonan portrays Jackson McLaren, contributing to the environment surrounding the astronauts' experiences.

Tom O'Brien
as Allen Dodge

Tom O'Brien plays Allen Dodge, a character involved in the mission's narrative.

Lucy Lin
as Shelly Carter

Lucy Lin portrays Shelly Carter, a supporting character who adds depth to the story.

Michael Crider
as Pat Elliott

Michael Crider plays Pat Elliott, a member of the cast depicted in various interactions.

Samantha Eggar
as Dr. Patraba
Rondi Reed
as Dr. Conlin
Conrad Bachmann
as Reporter
Sarah Dampf
as Paula, 2nd Grade Student
Charles Lanyer
as Spencer's Doctor
Gary Carlos Cervantes
as Doctor
Seth Barrish
as Yuppie Shark
Ellen Lancaster
as Dried Up Socialite
Julian Barnes
as Waiter
Priscilla Shanks
as Woman
Jennifer Burry
as Second Woman
Susan Cella
as Third Woman
Linda Powell
as Fourth Woman
Elston Ridgle
as Security Guard
Robert Sella
as Maitre D'
Samantha Carpel
as Reporter (Video)
Stephen Berger
as Doorman
Michael Luceri
as Waiter at Party
Ben Van Bergen
as Storage Facility Client
Edward Kerr
as Pilot
Cole Sprouse
as Twin
Dylan Sprouse
as Twin
Carl Burrows
as Businessman (uncredited)
Buck Holland
as Mission Control (uncredited)
Jacob Stein
as Calvin, 2nd Grade Student
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