The Substance Cast
The cast of The Substance including popularity data. Data for March 25, 2025.
Demi Moore
as Elisabeth Sparkle

Demi Moore plays Elisabeth Sparkle, a pivotal character in the movie.

#2
Most popular actor on The Substance
11,760 Wikipedia views yesterday
Margaret Qualley
as Sue

Margaret Qualley is Sue, another significant character in the storyline.

#1
Most popular actor on The Substance
16,008 Wikipedia views yesterday
Dennis Quaid
as Harvey

Dennis Quaid portrays Harvey, contributing to the film's overarching narrative.

#3
Most popular actor on The Substance
9,493 Wikipedia views yesterday
Gore Abrams
as Oliver

Gore Abrams takes on the role of Oliver, one of the key figures in the movie.

Hugo Diego Garcia
as Diego

Hugo Diego Garcia plays Diego, adding depth to the cast.

Olivier Raynal
as Alan

Olivier Raynal is Alan, a noteworthy character in the film.

Tiffany Hofstetter
as The Stylist

Tiffany Hofstetter plays The Stylist, contributing to the film's character dynamics.

Tom Morton
as The Doctor

Tom Morton portrays The Doctor, an important character in the plot.

Jiselle Burkhalter
as Girl

Jiselle Burkhalter takes on the role of Girl, playing a crucial part in the film.

Axel Baille
as The Photographer

Axel Baille is The Photographer, adding to the movie's intricate storyline.

Oscar Lesage
as Troy

Oscar Lesage portrays Troy, one of the significant characters in the film.

Matthew Géczy
as Bob Haswell

Matthew Géczy plays Bob Haswell, another key figure in the movie.

Philip Schurer
as Mr. Scream
Daniel Knight
as The Casting Director
Namory Bakayoko
as Silhouette
Bill Bentley
as Suit
Lucie Laffin
as Woman from the Public
Gregory Defleur
as Happy Birthday Person
For the best insights and data about The Substance, visit our main The Substance page.