Movies like The Substance

Requiem for a Dream explores the harrowing effects of addiction, echoing the themes of chemical dependency found in The Substance. The intense visual storytelling and haunting score create a visceral experience that is both captivating and disturbing.

Fear and Loathing in Las Vegas, based on Hunter S. Thompson's novel, offers a surreal and hallucinogenic view on a drug-fueled road trip. Its depiction of the chaotic and bizarre world under the influence makes it a fitting match for fans of The Substance.

Scarface examines the rise and fall of a drug kingpin, offering a dramatic portrayal of the narcotics underworld. Its intense and gripping narrative about power and addiction parallels the complex exploration of substances found in The Substance.

Trainspotting offers a gritty and stylized look into the lives of heroin addicts, much like the exploration of mind-altering substances in The Substance. Its colorful cast and kinetic direction make for a film that's both starkly real and wildly entertaining.

The Doors offers a biographical take on the iconic rock band, with a focus on lead singer Jim Morrison's experimentation with psychedelics. Its exploration of counterculture and drug use mirrors the themes explored in The Substance.

A Scanner Darkly dives into a dystopian future plagued by drug addiction and surveillance, similar to the themes in The Substance. The film's unique rotoscope animation brings an unsettling and dreamlike quality to this cautionary tale.