Cast of Transamerica

Felicity Huffman plays Sabrina 'Bree' Osbourne, a transgender woman who embarks on a cross-country journey to confront her past.

Kevin Zegers portrays Toby Wilkins, Bree's son, whom she discovers during her journey.

Fionnula Flanagan plays Elizabeth Schupak, Bree's estranged mother who has her own set of challenges.

Burt Young takes on the role of Murray Schupak, who represents Bree's troubled family dynamics.

Carrie Preston plays Sydney Schupak, Bree's supportive friend navigating the complexities of their relationship.

Elizabeth Peña portrays Margaret, a character that adds depth to Bree's journey.

Graham Greene plays Calvin Many Goats, giving insight into Bree’s interactions along her journey.

Venida Evans depicts Arletty, a character who crosses paths with Bree during her travels.

Jon Budinoff plays Alex, adding to the storyline of Bree's journey.

Raynor Scheine portrays Bobby Jensen, a character that Bree encounters in her quest.

Danny Burstein plays Dr. Spikowsky, a doctor involved in Bree's life.

Maurice Orozco plays Fernando, who is part of the storyline involving Bree.