The Serpent Queen (TV) Cast
The cast of The Serpent Queen. Updated on October 6, 2025.
40 actors
Samantha Morton
as Catherine de' Medici (8 episodes)

Samantha Morton portrays Catherine de' Medici, the resourceful and cunning Queen of France who navigates the turbulent political landscape of the 16th century.

Liv Hill
as Catherine de' Medici (8 episodes)

Liv Hill plays the young Catherine de' Medici, providing insight into her early life and the events that shape her future as a powerful queen.

Amrita Acharia
as Aabis (8 episodes)

Amrita Acharia portrays Aabis, a close companion and confidante within Catherine's court.

Barry Atsma
as Anne de Montmorency (8 episodes)

Barry Atsma is Anne de Montmorency, an influential figure in the French court and a trusted advisor.

Enzo Cilenti
as Cosimo Ruggeri (8 episodes)

Enzo Cilenti plays Cosimo Ruggeri, an astrologer whose counsel is sought by Catherine throughout her reign.

Sennia Nanua
as Rahima (8 episodes)

Sennia Nanua portrays Rahima, a servant in Catherine's court who experiences the intricacies of palace life.

Kiruna Stamell
as Mathilde (8 episodes)

Kiruna Stamell is Mathilde, whose role supports the narrative of life within the court.

Nicholas Burns
as Antoine de Bourbon (8 episodes)

Nicholas Burns plays Antoine de Bourbon, a member of the French nobility with interests in the power dynamics of the time.

Beth Goddard
as Antoinette de Bourbon (8 episodes)

Beth Goddard is Antoinette de Bourbon, navigating her position within the intricate power structures of the French court.

Raza Jaffrey
as Francis de Guise (8 episodes)

Raza Jaffrey portrays Francis de Guise, a prominent nobleman involved in the political machinations of the era.

Danny Kirrane
as Louis de Bourbon (8 episodes)

Danny Kirrane plays Louis de Bourbon, whose actions influence the course of events at court.

Ray Panthaki
as Charles de Lorraine (8 episodes)

Ray Panthaki is Charles de Lorraine, involved in the political and religious disputes of the time.

Paul Chahidi
as Charles de Bourbon (1 episode)
Navid Negahban
as Claude de Lorraine (1 episode)
Alex Heath
as Henry II of France (1 episode)
Ruby Bentall
as Angelica (1 episode)
Louis Landau
as Francis III of Brittany (1 episode)
Naomi Battrick
as Anne de Pisseleu d'Heilly (1 episode)
Colm Meaney
as Francis I of France (1 episode)
Charles Dance
as Clement VII (1 episode)
Adam Garcia
as Sebastiano de Montecuccoli (1 episode)
Rebecca Gethings
as Eleanor of Austria (1 episode)
Memet Ali Alabora
as Suleiman I of Turkey (1 episode)
Gemma Dobson
as Nathalie (1 episode)
Anna Cottis
as Cook (1 episode)
Ludivine Sagnier
as Diane de Poitiers (3 episodes)
Delcho Koprivshki
as Lorenzo de' Medici (1 episode)
Pierre Cevaer
as Footman (1 episode)
Loïc Azorin
as Footman (1 episode)
David Pearse
as Cardinal (1 episode)
Raphael Roger Levy
as Leader of Soldiers (1 episode)
Lucy Edkins
as Mother Superior (1 episode)
Antonin Totot
as Catherine's Guard (1 episode)
Nicolas Buchoux
as Doctor (Pope) (1 episode)
Carlotta Moraru
as Prostitute (1 episode)
Barbara Laurent
as Prostitute (1 episode)
Simon Parmentier
as Antoine de Bourbon (1 episode)
Nathan Parent
as Louis de Bourbon (1 episode)
Adam Amara
as Francis de Guise (1 episode)
Louis Pencréac'h
as Charles de Lorraine (1 episode)
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