Eddie, portrayed by Sean Penn, is a struggling casting director who is dealing with substance abuse issues and relationship challenges.
Kevin Spacey plays Mickey, a successful casting agent entangled in a toxic relationship with his girlfriend and friends.
Robin Wright portrays Darlene, a troubled young woman who becomes involved in the chaotic lives of the main characters.
Chazz Palminteri embodies Phil, a tough-talking and confrontational friend within the group.
Garry Shandling plays Artie, a friend of the main characters who tries to navigate the difficult dynamics of the group.
Anna Paquin portrays Donna, a young woman caught up in the turbulent world of her older friends.
Meg Ryan plays Bonnie, a complex character entwined in the troubled relationships of the main group.
Gianna Palminteri appears as Susie, a supporting character within the intertwined lives of the main cast.
David Fabrizio takes on the role of Store Manager, a minor character in the world of the main protagonists.
Kenny Vance appears as Singer, adding a musical element to the narrative of Hurlyburly.
Michaline Babich portrays Receptionist, a small role contributing to the depiction of the main characters' environment.
Elaine Corral Kendall appears as TV Anchor, providing a glimpse into the media world surrounding the characters in Hurlyburly.
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