Tom Hanks portrays the protagonist, Joe Banks, a man who embarks on a journey to a volcano as part of a mysterious adventure.
Meg Ryan takes on the roles of DeDe, Angelica, and Patricia Graynamore, playing multiple characters who play integral parts in Joe's journey.
Lloyd Bridges appears as Samuel Harvey Graynamore, a key figure in the story who sets Joe off on his path towards the volcano.
Dan Hedaya plays Frank Waturi, a character who interacts with Joe at the beginning of his journey and influences his decisions.
Ossie Davis portrays Marshall, a supporting character who provides guidance and wisdom to Joe during his adventures.
Barry McGovern appears as the Luggage Salesman, a brief but memorable character who crosses paths with Joe during his travels.
Robert Stack takes on the role of Dr. Ellison, a character who plays a small but significant part in Joe's journey towards self-discovery.
Amanda Plummer portrays Dagmar, a character with a mysterious allure who adds depth to Joe's adventures.
Lala Sloatman appears as the Waitress, a minor character who interacts with Joe during a crucial moment in the story.
Abe Vigoda plays the Chief of the Waponis, a character who represents a unique community that Joe encounters on his journey.
Carol Kane takes on the role of the Hairdresser, a character who provides a comedic element to Joe's adventures.
Branscombe Richmond appears as a Waponi, adding to the mystique of the community that Joe encounters on his quest.
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