Cast of Jungle 2 Jungle

Tim Allen stars as Michael Cromwell, a New York businessman who travels to the Amazon and discovers he has a teenage son.

Martin Short plays the role of Richard Kempster, Michael's quirky business partner.

JoBeth Williams portrays Dr. Patricia Cromwell, Michael's ex-wife and a caring mother.

Lolita Davidovich appears as Charlotte, Michael's girlfriend who questions his sudden fatherhood.

Sam Huntington takes on the role of Mimi-Siku, Michael's son from the Amazon jungle.

David Ogden Stiers is Alexei Jovanovic, a Russian businessman in the jungle who aids Michael.

Bob Dishy portrays George Langston, a friend of Michael in the business world.

Valerie Mahaffey plays Jan Kempster, Richard's wife and a support system for Michael.

Leelee Sobieski is Karen Kempster, Richard and Jan's daughter who forms a bond with Mimi-Siku.

Frankie J. Galasso appears as Andrew Kempster, Richard and Jan's son who also interacts with Mimi-Siku.

Luis Ávalos plays Abe, a friend of Michael in the Amazon who helps guide him.

Carole Shelley portrays Fiona, Richard's mother who brings comedic moments to the story.