Chris Cooper portrays Joe Kenehan, a union organizer who arrives in the town of Matewan to support the striking coal miners.
James Earl Jones plays 'Few Clothes' Johnson, a seasoned miner who is involved in the labor disputes in Matewan.
Mary McDonnell takes on the role of Elma Radnor, a local woman who becomes involved in the miners' fight for better working conditions.
Will Oldham plays Danny Radnor, Elma's younger brother who also joins the miners in their struggle.
David Strathairn portrays Police Chief Sid Hatfield, a key figure in the conflict between the miners and the coal company.
Ken Jenkins takes on the role of Sephus Purcell, another miner who stands with his fellow workers in Matewan.
Kevin Tighe plays Hickey, a character caught in the middle of the tensions between the miners and the coal company.
Gordon Clapp portrays Griggs, a member of the mining community who supports the efforts to unionize.
Bob Gunton plays C.E. Lively, a company man who represents the interests of the coal company in Matewan.
Jace Alexander takes on the role of Hilllard Elkins, a character involved in the struggles and conflicts within the mining community.
Joe Grifasi portrays Fausto, a miner who joins his colleagues in the fight against oppressive working conditions.
Nancy Mette plays Bridey Mae Tolliver, a woman impacted by the events surrounding the labor disputes in Matewan.
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