Jason Beghe plays Allan Mann, the quadriplegic protagonist who forms a strong connection with his trained monkey helper.
John Pankow portrays Geoffrey Fisher, a friend of Allan Mann who becomes entangled in the sinister events surrounding the monkey.
Kate McNeil takes on the role of Melanie Parker, a love interest of Allan Mann who gets caught up in the gripping story.
Joyce Van Patten stars as Dorothy Mann, Allan's concerned mother who worries about his well-being.
Christine Forrest plays Maryanne Hodges, another key character in the unfolding drama surrounding Allan and his monkey.
Stephen Root portrays Dean Burbage, adding depth to the narrative with his performance.
Stanley Tucci takes on the role of Dr. John Wiseman, a character intertwined with Allan's journey.
Tom Quinn plays Charlie Cunningham, a character who contributes to the tension and suspense in the movie.
Janine Turner portrays Linda Aikman, adding another layer to the cast of characters in Monkey Shines.
William Newman stars as Doc Williams, bringing his own unique touch to the film.
Tudi Wiggins takes on the role of Esther Fry, a character who plays a part in the unfolding events.
Patricia Tallman appears as a Party Guest, adding to the atmosphere and intrigue of the movie.
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