Robin Williams plays Seymour Parrish, a lonely photo technician who becomes obsessed with a family whose pictures he develops.
Connie Nielsen portrays Nina Yorkin, the mother in the family that Seymour becomes fixated on.
Michael Vartan plays Will Yorkin, Nina's husband, who is also the subject of Seymour's obsession.
Gary Cole takes on the role of Bill Owens, the store manager where Seymour works.
Erin Daniels plays Maya Burson, a colleague of Seymour at the photo development store.
Clark Gregg portrays Detective Paul Outerbridge, who investigates the events surrounding Seymour.
Nick Searcy plays the Repairman, who interacts with Seymour at the photo lab.
Dylan Smith plays Jake Yorkin, the son of Nina and Will Yorkin, who Seymour watches grow up through photographs.
Eriq La Salle portrays Detective James Van Der Zee, who is part of the investigation into Seymour's actions.
Paul Kim Jr. plays Yoshi Araki, a character in the photo development store.
Lee Garlington takes on the role of a Waitress in a scene where Seymour interacts with the public.
Marion Calvert plays Mrs. Von Unwerth, a character that appears in Seymour's life.
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