Cast of One True Thing

Meryl Streep plays Kate Gulden, a wife and mother who faces a life-threatening illness, prompting her daughter to reevaluate their relationship.

Renée Zellweger portrays Ellen Gulden, a young woman who must navigate her mother's illness while trying to find her own path in life.

William Hurt takes on the role of George Gulden, the husband of Kate and father of Ellen, whose family dynamics are tested during a challenging time.

Tom Everett Scott plays Brian Gulden, the son of Kate and George, who struggles to cope with the unfolding events within his family.

Lauren Graham appears as Jules, a character who interacts with the Gulden family and plays a part in their journey of self-discovery.

Nicky Katt portrays Jordan Belzer, a person connected to the family whose presence influences the unfolding events in their lives.

James Eckhouse appears as the District Attorney in the movie, a minor character who plays a role in the legal aspects of the narrative.

Patrick Breen takes on the role of G.A. Tweedy, a character who contributes to the story's themes and the family's emotional journey.

Gerrit Graham portrays Oliver Most, a character whose interactions with the Gulden family shed light on their dynamics and personal growth.

David Byron appears as Senator Sullivan, a character with a minor role in the narrative, adding a political dimension to the story.

Stephen Peabody plays Harold, a minor character who contributes to the setting and background of the family's experiences.

Lizbeth MacKay takes on the role of Dr. Cohen, a character involved in the medical aspect of the storyline, providing support and information.