Splice

Splice is a 2009 science fiction horror film directed by Vincenzo Natali, featuring Adrien Brody, Sarah Polley, and Delphine Chanéac. The story revolves around rebellious scientists who conduct a risky experiment by combining human and animal DNA to create a unique organism named Dren. This results in the creation of a captivating yet perilous winged human-chimera, leading to unpredictable and lethal consequences.