Michael Douglas plays Charles Remington, a big game hunter who assists Col. Patterson in dealing with the lions.
Val Kilmer portrays Col. John Henry Patterson, the engineer who leads the project to build a bridge and confronts the lion threats.
Tom Wilkinson takes on the role of Sir Robert Beaumont, who oversees the railway project and supports Patterson.
John Kani plays Samuel, a local worker who provides assistance and guidance to Patterson and Remington.
Emily Mortimer portrays Helena Patterson, the wife of Col. Patterson, who faces the challenges of their dangerous environment.
Bernard Hill plays Dr. David Hawthorne, the medical officer who aids the expeditions and addresses injuries.
Brian McCardie portrays Angus Starling, a member of the team involved in the railway project.
Om Puri plays Abdullah, a character who interacts with the main characters in the story.
Henry Cele takes on the role of Mahina, a significant figure in the local community.
Kurt Egelhof portrays the Indian Victim, one of the unfortunate victims of the lions.
Satchu Annamalai plays a Worker, contributing to the efforts of the railway construction.
Teddy Reddy also plays a Worker, assisting in various roles within the project.
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