Dan Aykroyd plays Roman Craig, the wealthy and somewhat arrogant brother-in-law of Chet Ripley.
John Candy portrays Chet Ripley, a family man who is eager to have a relaxing vacation with his loved ones.
Stephanie Faracy plays Connie Ripley, the supportive and caring wife of Chet Ripley.
Annette Bening portrays Kate Craig, Roman Craig's wife who brings humor and warmth to the story.
Chris Young plays Buck Ripley, the adventurous teenage son of Chet and Connie Ripley.
Lucy Deakins portrays Cammie, the daughter of Chet and Connie Ripley who has her own interests and challenges.
Robert Prosky plays Wally, a local character who interacts with the visiting families.
Ian Giatti portrays Ben Ripley, the younger son of Chet and Connie Ripley.
Hilary Gordon plays Cara Craig, the daughter of Roman and Kate Craig.
Rebecca Gordon portrays Mara Craig, another daughter of Roman and Kate Craig.
Zoaunne LeRoy plays Juanita, adding to the local flavor of the community.
Nancy Lenehan portrays a waitress who serves the characters during their vacation.
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