Andrew McCarthy stars as Larry Wilson, one of the main protagonists who, along with his friend Richard, gets caught up in a weekend of chaos after their boss Bernie suddenly dies.
Jonathan Silverman portrays Richard Parker, Larry's friend, and co-worker who, along with Larry, tries to hide the fact that their boss Bernie is dead to avoid getting in trouble.
Catherine Mary Stewart plays Gwen Saunders, a love interest of one of the main characters who gets unwittingly involved in the weekend shenanigans at Bernie's beach house.
Terry Kiser delivers a memorable performance as Bernie Lomax, the deceased boss whose body is manipulated by Larry and Richard to give the appearance that he is still alive.
Don Calfa appears as Paulie, one of Vito's hitmen who gets entangled in the chaotic events at Bernie's beach house.
Catherine Parks plays Tina, one of Vito's girls, who also finds herself inadvertently involved in the unfolding mayhem.
Eloise DeJoria takes on the role of Tawny, a character caught up in the comical situations that arise during the weekend at Bernie's beach house.
Gregory Salata portrays Marty, a secondary character who interacts with Larry and Richard during the hilarious events that unfold at Bernie's beach house.
Louis Giambalvo appears as Vito, a key figure whose connections and actions contribute to the escalating chaos at Bernie's beach house.
Ted Kotcheff makes a cameo as Jack Parker, a minor character who plays a part in the comedic misunderstandings that occur during the weekend at Bernie's beach house.
Margaret Hall has a small role as the Secretary, a character who interacts briefly with Larry and Richard, adding to the humor of the situations at Bernie's beach house.
Timothy Perez appears as the Mugger, a peripheral character who briefly crosses paths with the main characters at Bernie's beach house, adding to the chaos of the weekend.
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