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You, Me and Dupree

You, Me and Dupree Cast

42 cast members · 18 with popularity data
#5,302 movie today
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Most Popular You, Me and Dupree Cast Members

Michael Douglas is currently the most popular You, Me and Dupree cast member online with an Attention Score of 29.9. 4 of 42 cast members rank in the top 1,000 actors online today. Updated October 31, 2026.

1
Michael Douglas
Mr. Thompson
29.9
#20 overall
2
Owen Wilson
Dupree
10.1
#235 overall
3
Kate Hudson
Molly
6.4
#577 overall
4
Seth Rogen
Neil
5.8
#689 overall
5
Bill Hader
Mark
4.2
#1,260 overall
6
Todd Stashwick
Tony
3.3
#1,802 overall
7
Matt Dillon
Carl
3.1
#1,933 overall
8
Harry Dean Stanton
Curly (uncredited)
2.9
#2,138 overall
9
Lance Armstrong
Lance Armstrong
1.1
#6,264 overall
10
Billy Gardell
Bartender Dave
0.6
#9,654 overall
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11
Tasha Smith
Co-Worker (uncredited)
0.6
#10,683 overall
12
Amanda Detmer
Annie
0.3
#17,546 overall
13
Pat Crawford Brown
Aunt Kathy
0.1
#26,139 overall
14
Joe Russo
Personnel Manager
0.1
#29,512 overall
15
Michelle Lee
Hawaiian Air Ticketing Agent (uncredited)
0.1
#36,137 overall
16
Summer Altice
Stripper
0.0
#43,974 overall
17
Jason Winer
Eddie
0.0
#47,312 overall
18
Sidney S. Liufau
Paco
0.0
#47,777 overall
19
Ralph Ting
Toshi
—
20
Eli Vargas
Aaron
—
21
Houston Mack
Dougie
—
22
Bob Larkin
Army Veteran
—
23
Suzanne Ford
Thompson's Secretary
—
24
Claudia Choi
Carl's Secretary
—
25
Jeanine Hass
Stripper
—
26
Peter Ruocco
Wedding Planner
—
27
Lance Irwin
Neighborhood Father
—
28
Fenessa Pineda
2nd Grade Girl
—
29
Joe Russo
Personnel Manager
—
30
Mario Revolori
2nd Grade Boy
—
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31
Jay Lembeck
Minister
—
32
Gil Harris
Reese
—
33
Bayani Ison
Hawaiian Bartender
—
34
Joe Wilson
Joe
—
35
Blaine Pate
Larry
—
36
Kevin Breznahan
Charlie
—
37
Trevor Stock
Herb
—
38
Sean Perrone
Ned
—
39
Craig Hosking
Pilot
—
40
Amber Hay
Wedding Guest (uncredited)
—
41
Kepa Kruse
Waiter (uncredited)
—
42
May Porter
Waitress (uncredited)
—
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