You, Me and Dupree Cast
The cast of You, Me and Dupree including popularity data. Data for January 20, 2025.
ActorImage
Owen Wilson
as Dupree

Portrayed the character Dupree.

#2
Most popular actor on You, Me and Dupree
7,144 Wikipedia views yesterday
ActorImage
Kate Hudson
as Molly

Portrayed the character Molly.

#4
Most popular actor on You, Me and Dupree
6,801 Wikipedia views yesterday
ActorImage
Matt Dillon
as Carl

Portrayed the character Carl.

#5
Most popular actor on You, Me and Dupree
5,377 Wikipedia views yesterday
ActorImage
Michael Douglas
as Mr. Thompson

Portrayed the character Mr. Thompson.

#1
Most popular actor on You, Me and Dupree
8,127 Wikipedia views yesterday
ActorImage
Seth Rogen
as Neil

Portrayed the character Neil.

#6
Most popular actor on You, Me and Dupree
5,064 Wikipedia views yesterday
ActorImage
Amanda Detmer
as Annie

Portrayed the character Annie.

#11
Most popular actor on You, Me and Dupree
733 Wikipedia views yesterday
ActorImage
Bill Hader
as Mark

Portrayed the character Mark.

#7
Most popular actor on You, Me and Dupree
4,889 Wikipedia views yesterday
ActorImage
Todd Stashwick
as Tony

Portrayed the character Tony.

#12
Most popular actor on You, Me and Dupree
254 Wikipedia views yesterday
ActorImage
Ralph Ting
as Toshi
ActorImage
Lance Armstrong
as Self
#8
Most popular actor on You, Me and Dupree
2,002 Wikipedia views yesterday
ActorImage
Suzanne Ford
as Thompson's Secretary
ActorImage
Claudia Choi
as Carl's Secretary
ActorImage
Eli Vargas
as Aaron
ActorImage
Amber Hay
as Wedding Guest (uncredited)
ActorImage
Harry Dean Stanton
as Curly (uncredited)
#3
Most popular actor on You, Me and Dupree
7,046 Wikipedia views yesterday
ActorImage
Jason Winer
as Eddie
ActorImage
Sidney S. Liufau
as Paco
#16
Most popular actor on You, Me and Dupree
15 Wikipedia views yesterday
ActorImage
Billy Gardell
as Bartender Dave
#9
Most popular actor on You, Me and Dupree
1,412 Wikipedia views yesterday
ActorImage
Houston Mack
as Dougie
ActorImage
Bob Larkin
as Army Veteran
#17
Most popular actor on You, Me and Dupree
5 Wikipedia views yesterday
ActorImage
Summer Altice
as Stripper
#14
Most popular actor on You, Me and Dupree
72 Wikipedia views yesterday
ActorImage
Jeanine Hass
as Stripper
ActorImage
Peter Ruocco
as Wedding Planner
ActorImage
Joe Russo
as Personnel Manager
ActorImage
Lance Irwin
as Neighborhood Father
ActorImage
Fenessa Pineda
as 2nd Grade Girl
#15
Most popular actor on You, Me and Dupree
45 Wikipedia views yesterday
ActorImage
Mario Revolori
as 2nd Grade Boy
ActorImage
Jay Lembeck
as Minister
ActorImage
Gil Harris
as Reese
ActorImage
Pat Crawford Brown
as Aunt Kathy
#13
Most popular actor on You, Me and Dupree
107 Wikipedia views yesterday
ActorImage
Bayani Ison
as Hawaiian Bartender
ActorImage
Joe Wilson
as Joe
ActorImage
Blaine Pate
as Larry
ActorImage
Kevin Breznahan
as Charlie
ActorImage
Trevor Stock
as Herb
ActorImage
Sean Perrone
as Ned
ActorImage
Craig Hosking
as Pilot
ActorImage
Kepa Kruse
as Waiter (uncredited)
ActorImage
Michelle Lee
as Hawaiian Air Ticketing Agent (uncredited)
ActorImage
May Porter
as Waitress (uncredited)
ActorImage
Tasha Smith
as Co-Worker (uncredited)
#10
Most popular actor on You, Me and Dupree
1,240 Wikipedia views yesterday
For the best insights and data about You, Me and Dupree, visit our main You, Me and Dupree page.