A.P. Bio (TV) Cast Popularity
The cast of A.P. Bio including daily popularity data. Updated on May 29, 2025.
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146 total actors
Glenn Howerton
as Jack Griffin (42 episodes)

Glenn Howerton plays Jack Griffin, an ex-philosophy professor who teaches A.P. Bio.

#1
Most popular actor on A.P. Bio
12,080 Wikipedia views yesterday
Lyric Lewis
as Stef (42 episodes)

Lyric Lewis portrays Stef, one of the enthusiastic teachers at Whitlock High School.

Mary Sohn
as Mary (42 episodes)

Mary Sohn plays Mary, a high-spirited teacher at the school.

Jean Villepique
as Michelle (42 episodes)

Jean Villepique is Michelle, another vibrant teacher at Whitlock High.

#36
Most popular actor on A.P. Bio
91 Wikipedia views yesterday
Tom Bennett
as Miles (13 episodes)

Tom Bennett takes on the role of Miles, Jack's rival.

Patton Oswalt
as Principal Durbin (42 episodes)

Patton Oswalt is Principal Durbin, the well-meaning principal of Whitlock High.

#5
Most popular actor on A.P. Bio
2,486 Wikipedia views yesterday
Aparna Brielle
as Sarika (42 episodes)

Aparna Brielle plays Sarika, a brilliant student in Jack's class.

#18
Most popular actor on A.P. Bio
426 Wikipedia views yesterday
Sari Arambulo
as Grace (42 episodes)

Sari Arambulo portrays Grace, a student in the A.P. Bio class.

Paula Pell
as Helen Henry Demarcus (37 episodes)

Paula Pell plays Helen Henry Demarcus, the secretary at Whitlock High.

#14
Most popular actor on A.P. Bio
630 Wikipedia views yesterday
Niecy Nash-Betts
as Kim (1 episode)
#9
Most popular actor on A.P. Bio
1,422 Wikipedia views yesterday
Ronnie Alvarez
as Waiter (1 episode)

Ronnie Alvarez appears as the Waiter.

Tim Heidecker
as Greg Miller (1 episode)

Tim Heidecker plays Greg Miller.

#11
Most popular actor on A.P. Bio
886 Wikipedia views yesterday
Taran Killam
as Mr. Vining (1 episode)
#6
Most popular actor on A.P. Bio
2,172 Wikipedia views yesterday
Saidah Arrika Ekulona
as School Board Beth (1 episode)
Mark Proksch
as Philip (1 episode)
#13
Most popular actor on A.P. Bio
645 Wikipedia views yesterday
Tim Lounibos
as Cliff (1 episode)
Nikki Glaser
as Chloe (1 episode)
#3
Most popular actor on A.P. Bio
3,038 Wikipedia views yesterday
Eden Riegel
as Katie (1 episode)
#21
Most popular actor on A.P. Bio
290 Wikipedia views yesterday
Kalpana Pot
as Nice Woman #2 (1 episode)
Rheagan Wallace
as Nice Woman #1 (1 episode)
#38
Most popular actor on A.P. Bio
44 Wikipedia views yesterday
Emily Tuñon
as Vicky (1 episode)
Kelli Dawn Hancock
as Bartender (1 episode)
Stanley Ullman
as Bus Driver (1 episode)
Erinn Hayes
as Trish (1 episode)
#16
Most popular actor on A.P. Bio
467 Wikipedia views yesterday
Lisa Loeb
as Lisa Loeb (1 episode)
#12
Most popular actor on A.P. Bio
756 Wikipedia views yesterday
Anjali Bhimani
as Sarika's Mom (1 episode)
#27
Most popular actor on A.P. Bio
187 Wikipedia views yesterday
Lori Alan
as Didi (2 episodes)
#22
Most popular actor on A.P. Bio
273 Wikipedia views yesterday
Rebecca Sohn
as Prude Mom (1 episode)
Dominique Morton
as Angry Student (1 episode)
Steve Jones
as Steve Jones (1 episode)
Bill Nye
as Bill Nye (1 episode)
#8
Most popular actor on A.P. Bio
1,612 Wikipedia views yesterday
Flavor Flav
as Flavor Flav (1 episode)
#7
Most popular actor on A.P. Bio
1,750 Wikipedia views yesterday
Will Greenberg
as Dave Eggleston (1 episode)
Jonathan T. Floyd
as Repairman (1 episode)
Eric Normington
as Publishing Executive (1 episode)
Andrew Hansen
as Tech Guy (1 episode)
#39
Most popular actor on A.P. Bio
40 Wikipedia views yesterday
Mike O'Gorman
as Chase (1 episode)
Clayton English
as David (1 episode)
Jason Huber
as Victor's Dad (1 episode)
Samantha Follows
as Victor's Mom (1 episode)
Michael Gross
as Brandon (1 episode)
Tricia O'Kelley
as Sadie (1 episode)
#32
Most popular actor on A.P. Bio
142 Wikipedia views yesterday
Collette Wolfe
as Meredith (3 episodes)
#19
Most popular actor on A.P. Bio
392 Wikipedia views yesterday
Angela Kinsey
as Brenda (1 episode)
#10
Most popular actor on A.P. Bio
1,210 Wikipedia views yesterday
Zach Reino
as Chops (1 episode)
Kaison Prince William
as Jeffy (1 episode)
Brianne Tju
as Dallas (1 episode)
#23
Most popular actor on A.P. Bio
270 Wikipedia views yesterday
John D'Aquino
as Dean Warren Richardson (1 episode)
#25
Most popular actor on A.P. Bio
241 Wikipedia views yesterday
Xander Evans
as Russian Student (1 episode)
Jane Morris
as Rhonda (1 episode)
Tate Birchmore
as Young Jack (1 episode)
Susan James Berger
as Dollhouse Lady (1 episode)
Hadiyah Robinson
as Mrs. Baxter (1 episode)
Jon Lovitz
as Robin Schwonk (1 episode)
#4
Most popular actor on A.P. Bio
2,513 Wikipedia views yesterday
Sohm Kapila
as Meena (1 episode)
Matthew Campbell Dowling
as Waiter (1 episode)
Hans Holsen
as Ron (1 episode)
Bryan Michael Nunez
as Travis (1 episode)
Marina Shtoda
as Dale's Wife (1 episode)
Cullen G. Chambers
as Mr. On-Your-Left (1 episode)
Laird Macintosh
as Mark (1 episode)
#40
Most popular actor on A.P. Bio
29 Wikipedia views yesterday
Maria Christina Thayer
as Molly (1 episode)
Denisse Ojeda
as Erica (1 episode)
Jill Czarnowski
as Mom (1 episode)
Gilbert James Talbot
as Don Chacho (1 episode)
Ruben Dario
as Dad (1 episode)
Aidan Bertola
as Kid (1 episode)
Kellee Stewart
as Marjorie (1 episode)
#31
Most popular actor on A.P. Bio
147 Wikipedia views yesterday
Karly Rothenberg
as Agatha (1 episode)
#42
Most popular actor on A.P. Bio
23 Wikipedia views yesterday
Kendra Munger
as Dr. Gordon (1 episode)
Ron Funches
as Hans (2 episodes)
#15
Most popular actor on A.P. Bio
540 Wikipedia views yesterday
Lilián García
as Ring Announcer (1 episode)
Jordan Ghaim
as Fanatic #1 (1 episode)
Calder Holbrook
as Fanatic #2 (1 episode)
Aron Stevens
as Tennessee Ronnie Log (1 episode)
#24
Most popular actor on A.P. Bio
253 Wikipedia views yesterday
Elizabeth Guest
as Gretchen (1 episode)
Rick Overton
as House Father (1 episode)
#34
Most popular actor on A.P. Bio
106 Wikipedia views yesterday
Pat McNeely
as Mrs. Goodman (1 episode)
Ed Taylor
as Bearded Man (1 episode)
Micaela Wittman
as Teenage Girl (1 episode)
#43
Most popular actor on A.P. Bio
8 Wikipedia views yesterday
Hope Shapiro
as Caleb's Mother (1 episode)
Elizabeth Phoenix Caro
as Young Girl (1 episode)
David Gborie
as Mr. McKinnon (1 episode)
Jessica Garza
as Mia Nunez (1 episode)
Cheryl Lynn Bowers
as Rosemary Griffin (3 episodes)
Douglas Bennett
as Bob (Jug Band Member) (1 episode)
John Pirruccello
as Principal Kling (1 episode)
Clint Culp
as Construction Worker (1 episode)
Meagen Fay
as Sister Frances (1 episode)
#26
Most popular actor on A.P. Bio
225 Wikipedia views yesterday
Nancy Friedrich
as Sister Monica (1 episode)
Dan Gilvary
as Priest (1 episode)
Justin Tinucci
as Bully (1 episode)
#46
Most popular actor on A.P. Bio
2 Wikipedia views yesterday
Tania Gunadi
as Sarah (1 episode)
#33
Most popular actor on A.P. Bio
142 Wikipedia views yesterday
Tiago Roberts
as Bachelor (1 episode)
Sam Lazarus
as Reporter (1 episode)
Arthur Keng
as Waiter (1 episode)
Jamila Webb
as Kelly (1 episode)
April Adams
as Mavis (1 episode)
#45
Most popular actor on A.P. Bio
3 Wikipedia views yesterday
Freedom Bridgewater
as Delivery Guy (1 episode)
Alfred Adderly
as EMT (1 episode)
For the best insights and data about the TV show A.P. Bio, visit our main A.P. Bio page.