Best Medicine cast
45 cast members · 5 main · 2 seasons · 2026–present45 cast members · 2 seasons
Abigail Spencer was the most popular Best Medicine cast member yesterday, at #923.Abigail Spencer leads the cast at #923.
Each rank is among everyone we track, by Attention Score, which measures how much attention a person gets online each day.Attention Score measures online attention. Learn more
Main cast
In at least half of the episodes
- Abigail Spenceras Louisa Glasson · 20 of 20 episodes20 eps#9234.6
- Annie Pottsas Aunt Joan · 20 of 20 episodes20 eps#1,0354.3
- Josh Charlesas Dr. Martin Best · 20 of 20 episodes20 eps#2,2552.6
- Josh Segarraas Sheriff Mark Mylow · 20 of 20 episodes20 eps#3,1442.0
- Creeas Elaine Denham · 20 of 20 episodes20 eps#4,7401.4
Recurring
In three or more episodes
- Eliza Coupeas Dr. Eden Montgomery / Eden Montgomery · 7 of 20 episodes7 eps#4,7991.3
- John DiMaggioas Bert Large · 4 of 20 episodes4 eps#5,6811.1
- Didi Connas Geneva · 3 of 20 episodes3 eps#7,2160.9
- Stephen Spinellaas Greg Garrison · 9 of 20 episodes9 eps#11,2240.5
- Clea Lewisas Sally Mylow · 3 of 20 episodes3 eps#15,9360.3
- Jason Veaseyas George Brady · 9 of 20 episodes9 eps
- Ben Lewis Dohertyas Peter Cronk · 7 of 20 episodes7 eps
- Carter Shimpas Al Large · 4 of 20 episodes4 eps
- Alison Cimmetas Irma · 3 of 20 episodes3 eps
Guest stars
One or two episodes
- Andrea Martinas Judith · 1 of 20 episode1 ep#1,4213.6
- Martin Clunesas Dr. Robert Best · 1 of 20 episode1 ep#5,1611.2
- Heléne Yorkeas Savannah Michaud · 1 of 20 episode1 ep#8,0420.8
- Wendy Makkenaas Susan Carlisle · 2 of 20 episodes2 eps#11,9540.5
- Michael Pottsas Gilbert Carlisle · 2 of 20 episodes2 eps#14,0900.4
- Nadia Dajanias Gina Marie Afragola · 1 of 20 episode1 ep#18,7980.2
- Gene Jonesas Old Man Collins · 2 of 20 episodes2 eps#23,9970.1
- Kathy Searleas Freda · 1 of 20 episode1 ep#60,2930.0
- Alexandra Sicaas Harley · 2 of 20 episodes2 eps
- Leah Janae Thomasas Amelia · 2 of 20 episodes2 eps
- Josh Hoon Leeas Liam · 2 of 20 episodes2 eps
- Adrian Enscoeas Doug · 1 of 20 episode1 ep
- Alexandria Benfordas Belinda · 1 of 20 episode1 ep
- Eston Fungas Ben · 1 of 20 episode1 ep
- Adam Shalzias Foot Fungus Bill · 1 of 20 episode1 ep
- Patch Darraghas Glendon Ross · 1 of 20 episode1 ep
- Ellen Nikbakhtas Cecilia · 1 of 20 episode1 ep
- Cindy De La Cruzas Jeannie · 1 of 20 episode1 ep
- Camren Carringtonas Faker Tommy · 1 of 20 episode1 ep
- Tiffany Denise Hobbsas Mom Mary · 1 of 20 episode1 ep
- Raka Deyas Renee · 1 of 20 episode1 ep
- Jon Okabayashias Clyde the Local Fisherman · 1 of 20 episode1 ep
- David Davinoas Fancy Customer Chuck · 1 of 20 episode1 ep
- Marta Kotzianas Fancy Customer Dolores · 1 of 20 episode1 ep
- Char Jonesas Bree · 1 of 20 episode1 ep
- Buzz Roddyas Larry Jackson · 1 of 20 episode1 ep
- Ellen Boscovas Coffee Karla · 1 of 20 episode1 ep
- Aidan Hartas Johnny aka Local Hoodlum · 1 of 20 episode1 ep
- Randy Donaldsonas Quincy aka Townsperson #1 · 1 of 20 episode1 ep
- Lily Gleasonas Mia · 1 of 20 episode1 ep
- Cal Tolentinoas Kyle · 1 of 20 episode1 ep
The cast, together again
Other titles with the most Best Medicine cast members
Cast questions
Who is the most popular Best Medicine cast member right now?
Abigail Spencer is currently the most popular Best Medicine cast member online, with an Attention Score of 4.6 and an overall rank of #923 as of November 6, 2026.
How many cast members does Best Medicine have?
Best Medicine has 45 credited cast members. 18 of them have an Attention Score on Television Stats today.
Which Best Medicine cast member has the biggest career high?
Abigail Spencer has the biggest career high among the Best Medicine cast, an Attention Score of 9.1 over their best 30 days.
How many Best Medicine cast members are in the top 1,000 people today?
1 of the 45 Best Medicine cast members currently rank within the top 1,000 most popular people online on Television Stats.