Danny Aiello portrays Dosmo Pizzo, a hitman with a philosophical side and a soft spot for a young girl.
Jeff Daniels plays Alvin Strayer, an erratic, chain-smoking detective focused on solving a murder case.
Teri Hatcher is Becky Foxx, a strong-willed but vulnerable woman caught in a dangerous love triangle.
Charlize Theron brings to life Helga Svelgen, a cold and calculating assassin with a complex past.
James Spader portrays Lee Woods, a skilled but troubled hitman dealing with personal demons.
Eric Stoltz plays Wes Taylor, a caring veterinarian who gets entangled in criminal activities.
Glenne Headly is Susan Parish, a nurse who becomes involved in a web of crime and intrigue.
Peter Horton portrays Roy Foxx, a former Olympic skier turned drug dealer seeking redemption.
Greg Cruttwell plays Allan Hopper, a manipulative art dealer with a dark secret.
Marsha Mason is Audrey Hopper, Allan's wealthy and disillusioned wife who finds herself in danger.
Paul Mazursky portrays Teddy Peppers, a jovial and chatty minor league baseball team owner.
Keith Carradine is Detective Creighton, a dedicated investigator working to solve a series of interconnected crimes.
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